Searchable abstracts of presentations at key conferences in endocrinology

ea0090p549 | Adrenal and Cardiovascular Endocrinology | ECE2023

Differentiation of Pluripotent Stem Cells into Steroidogenic Cells with the Application of Artificial Intelligence

Oikonomakos Ioannis , Sanabria Melissa , Neirijnck Yasmine , Bornstein Stefan , Schedl Andreas , Steenblock Charlotte

Adrenal insufficiency is a life-threatening condition in which the adrenal glands fail to produce adequate amounts of steroid hormones thus leading to severe disturbances of body homeostasis. Today’s treatment options are limited to hormone replacement therapies that are, however, hampered by serious side effects. Cell replacement therapies with adrenocortical stem cells could present a potential cure, but the culture of such stem cells has proven difficult. We have devel...